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Drug Delivery Systems

BD offers pharma and biotech companies a broad range of drug delivery solutions and services to help achieve goals.

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Overview

Why BD drug delivery systems?

Our ready-to-administer drug delivery systems, including prefillable syringes, self-injection systems, and safety and shielding devices, help ensure smooth delivery, regardless of drug complexity, viscosity and dosing volume.

Our prefillable syringes help reduce:

  • Medication errors
  • Syringe reuse
  • Microbial contamination
  • Steps to prepare injections
  • Drug waste3

Trusted Expertise

BD – An industry leader with broad expertise

  • 70%

    Providing systems for 70% of top 100 pharmaceutical companies around the world1

  • 500 companies

    Manufacturing containers for more than 500 pharmaceutical and biotech companies worldwide2

  • 100 molecules

    Leveraging experience with hundreds of molecules spanning a broad range of therapeutic areas

Our prefillable syringes help reduce:
Our prefillable syringes help reduce:
  • Medication errors
  • Syringe reuse
  • Microbial contamination
  • Steps to prepare injections
  • Drug waste3
Our self-injection systems help:
Our self-injection systems help:
  • Enable the transition of treatment from the hospital to the home
  • Increase patient adherence
  • Enable at-home injections, saving money and patients' time
  • Reduce the risk of needlestick injury4
Our safety and shielding devices* help reduce:
Our safety and shielding devices* help reduce:
  • Needlestick injury for healthcare workers and patients
  • Risk of health complications due to occupational bloodborne infections
  • Risk of syringe reuse
  • Ergonomic challenges with manual injection5

PATIENT BENEFITS

Keeping the focus on patients

BD drug delivery systems give patients confidence, freedom and safety—appreciated benefits when it comes to receiving the medications they need. Learn how these benefits support adherence.

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Convenience

Certain prefillable devices are designed to be safely used by patients in the comfort of their own home.6

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Intuitiveness

Prefilled systems are intuitive and easy to use for self-administration.3,6,7

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Dosing accuracy

Ready-to-administer systems ensure that the patient receives the right dose every time.3

OUR APPROACH

BD closely partners with you to fully understand the specific characteristics and requirements of your drug and your need. We then help you select and validate the optimal container and delivery system for it, leveraging our product features and designs to ensure our solutions fits your needs.

Providing experience that counts

Applying years of experience with hundreds of drug products, our dedicated Technical Services team draws from a product portfolio designed for varying drug properties and requirements to select and risk mitigate your prefillable syringes, self-injection systems, and safety and shielding solutions. We offer services to assist with formulation development, to predict and assess drug-container interactions, and to determine delivery feasibility and system performance.

Learn more about our services

Leveraging our integrated system approach

In our in-house, GMP-compliant laboratories, we advise and conduct system feasibility, performance and combination product testing with your drug. We also perform analytical chemistry testing such as stability studies and extractables and leachables.

Learn more about our technical services

Supporting you for a smooth registration process in your target markets

Our dedicated Regulatory Affairs team provides customized regulatory advice and documentation in alignment with worldwide filing requirements to support you in your registration process.

Learn more about our support in regulatory affairs

EXPLORE OUR PRODUCTS

Products for all drug delivery needs

Our portfolio is so extensive that whatever your drug product, we offer a solution that will optimally administer it.

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BD Hylok™ glass pre-fillable syringe

Certain prefillable devices are designed to be safely used by patients in the comfort of their own home.6

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BD Neopak™ glass pre-fillable syringe platform

Prefilled systems are intuitive and easy to use for self-administration.3,6,7

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BD UltraSafe Passive™ needle guard

Ready-to-administer systems ensure that the patient receives the right dose every time.3

State-of-the-art production and supply
State-of-the-art production and supply

We are equipped to meet your production and supply needs through our reliable supply chain system, dual sourcing of major components, safety stock, ability to minimize unexpected events and high-capacity manufacturing.

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World-class manufacturing
World-class manufacturing

BD maintains seven standardized plants worldwide, ensuring consistent quality and reporting. On a case-by-case basis, we take a customized approach to organize customer audits and site validations.

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Always advancing our pharmaceutical systems
Always advancing our pharmaceutical systems

BD continuously invests in our technology and infrastructure to deliver best-in-class product performance and services. Supported by our reliable and agile manufacturing network and dedicated Centers of Excellence, we are able to develop next-generation pharmaceutical systems to meet even the most rigorous demands in this rapidly evolving industry.

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Let’s have a conversation.

At BD, we’re committed to partnering with you to help solve your medication management challenges, so you can focus on delivering quality care. Are you ready to connect?

Contact Sales
Please fill out the form and a sales representive will get in touch with you.

Notes

* BD UltraSafe Passive™ needle guard and BD UltraSafe Plus™ passive needle guard
References
  1. IQVIA-based analysis and BD SAP ECC, SAP legacy, Tracis, Nodum systems [invoicing data]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2016.
  2. BD SAP ECC, SAP legacy, Tracis, Nodum systems [invoicing data]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2018.
  3. Benefits of BD prefilled syringes [value dossier]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2017.
  4. Barrow-Williams T, Burnell R. Autoinjectors: technology advances and market trends. Innovations in Pharmaceutical Technology. August 30, 2007. Accessed September 27, 2018.
  5. World Health Organization. WHO guideline on the use of safety-engineered syringes for intramuscular, intradermal and subcutaneous injection in health care settings. Published 2016. Accessed September 27, 2018.
  6. BD Hylok Human Factor study [Internal report]. Pont-de-Claix, FR: Becton Dickinson and Company; 2017.
  7. Schwarzenbach F, Trong MD, Grange L, et al. Results of a human factors experiment of the usability and patient acceptance of a new autoinjector in patients with rheumatoid arthritis. Patient Prefer Adherence. 2014;8:199-209.

References

  1. IQVIA-based analysis and BD SAP ECC, SAP legacy, Tracis, Nodum systems [invoicing data]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2016.
  2. BD SAP ECC, SAP legacy, Tracis, Nodum systems [invoicing data]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2018.
  3. Benefits of BD prefilled syringes [value dossier]. Franklin Lakes, NJ: Becton, Dickinson and Company; 2017.
  4. Barrow-Williams T, Burnell R. Autoinjectors: technology advances and market trends. Innovations in Pharmaceutical Technology. August 30, 2007. Accessed September 27, 2018.
  5. World Health Organization. WHO guideline on the use of safety-engineered syringes for intramuscular, intradermal and subcutaneous injection in health care settings. Published 2016. Accessed September 27, 2018.
  6. BD Hylok Human Factor study [Internal report]. Pont-de-Claix, FR: Becton Dickinson and Company; 2017.
  7. Schwarzenbach F, Trong MD, Grange L, et al. Results of a human factors experiment of the usability and patient acceptance of a new autoinjector in patients with rheumatoid arthritis. Patient Prefer Adherence. 2014;8:199-209.

About

Products

BD provides industry-leading needle technologies, prefillable syringes, safety and shielding systems, and self-injection systems for pharmaceutical and biotech companies across the globe.

Needle technologies

Take technical innovation to needle industrialization

BD utilizes leading-edge needle technologies to combine an optimal needle point and cannula for your drug's requirements. Working with you while offering expertise, we can select the needle from our wide range of offerings that ultimately give patients the best possible experience. We can also customize the needle gauge and length upon request.

Make a sharp choice for your needle

BD needle technologies are supported by clinical and manufacturing expertise. With BD needle technologies, customers enjoy the benefits of our clinical and manufacturing expertise.

Prefillable syringe systems

Let us focus on the details, down to the molecule

Whether for biologics, vaccines, anticoagulants, or small molecules and other specialties, our prefillable glass and polymer syringe systems can help effectively, reliably and consistently administer the drug therapy you provide. Using our resourcefulness with your input, we develop your system to optimize administration and differentiate your drug—an imperative in today's competitive marketplace.

Fulfill your expectations with our pre-fillable solutions

Whatever drug therapy you provide, you gain the benefit of our expertise with how drugs interact with containers, with what primary containers are right for different drugs, and if relevant, with how to effectively integrate containers or devices.

Safety and shielding systems

Protect against injury with a full shielding solution

BD offers a wide range of safety and shielding systems that feature innovative needle shielding system technology for your injectable drug. With our proprietary systems, you can help prevent the continuously increasing risks and costs of needlestick injuries that are leading government agencies to enforce more stringent legislation.1

Self-injection systems

Innovate self-injections to enhance the patient experience

Your drug impacts patients' lives and healthcare professionals' approaches to treatment. We understand that, which is why we partner with you to develop self-injection systems that address your drug delivery concerns while incorporating design factors to meet patient needs.

We provide the flexible manufacturing, customization, drug compatibility and seamless integration that combination products require today to succeed. We help you accelerate delivery time, so you can promptly take your drug to market while reducing risk—for the benefit of your company, your customers and your partners.

Give your patients confidence in their self-administration

A global leader in self-injection systems, BD offers a differentiated solution and a full portfolio of self-injection systems designed for the patient and developed with modular platform technology that enables us to rapidly customize your product and aims to accelerate its time to market.

About

Capabilities

We are committed to building partnership with you and developing product solutions that meet your needs by leveraging our innovative technologies and extensive global manufacturing

Addressing your needs

At BD, we strategically develop our solutions to mitigate risks associated with combination product development and medication administration to enhance the certainty of safe and sound drug delivery.

 


PRODUCT DEVELOPMENT SUPPORT

Capabilities that simplify complexities

By partnering with BD for strategic support, you can minimize risk while avoiding delays in combination product development.

Our prefillable syringes help reduce:

  • Medication errors
  • Syringe reuse
  • Microbial contamination
  • Steps to prepare injections
  • Drug waste3

 

 

MEDICATION DELIVERY SUPPORT

Functionality you can take comfort in Partnering with BD can help you circumvent common issues that occur in medication delivery.

Delivery system performance
Delivery system performance

Our product portfolio reduces the risk of combination product performance issues by supporting complex and challenging drug formulations, larger injection volumes and higher viscosities. Our integrated primary containers and secondary systems—integrated by design—can help you reduce development risk and improve system performance.

For Infection Preventionists
For Infection Preventionists

Challenge

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How bd can help

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For Infection Preventionists
For Infection Preventionists

Challenge

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How bd can help

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For Infection Preventionists
For Infection Preventionists

Challenge

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How bd can help

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System Integration

Customer Benefits

As your partner, we leverage our deep industry expertise to help enhance device related aspects of your combination product's development. Through our robust data and supportive evidence, we provide critical insights to help your combination product get to market on time.

At BD, we know that total system integration – where your drug formulation, primary container and secondary device require reliable combination to deliver dependable performance under real-life conditions – is critical to getting your drug to market quickly, efficiently and safely. To give you every advantage, we will help you anticipate and address a range of needs, from human factors aspects and use-related hazards to the complex regulatory environment.6,7

SYSTEM INTEGRATION SUPPORT

BD capabilities can support you combination development means.

Patient safety is our top priority. As such our innovation process begins with patient requirements and is enhanced by our vast experience, providing integral insights to help support the success of your drug in the market.1,4 Our design considers human factors to help your combination product provide a positive injection experience. Our advanced drug delivery systems aim to support enhanced:

  • Patient safety
  • Comfort6,7
  • Adherence

 

Insights on patient resource links:

Meeting requirements for human factors considerations (OnDrug Delivery, 2018) >

In drug development, project delays can equal meaningful increases in costs that can impact your profitability and the viability of bringing your drug to market.5 Our goal is to help you anticipate obstacles, mitigate risks and solve for operational challenges, so your combination product meets timelines and performs under real-life conditions. BD can help augment your combination development capabilities and support efficiency through:

  • Reliable performance during fill, finish and assembly to minimize operational expenses and waste
  • Reproducible performance across millions of units. From 2010 through 2018, BD has received less than 3 reported complaints per million associated with system integration for BD Physioject™ disposable autoinjector annually.2 At BD, we take complaints seriously but also as an opportunity to understand how that product is performing in a final combination product or as a subsystem with other systems. This experience strengthens our expertise to support and help de-risk future combination product development.

Launching a combination product can come with many challenges.5 As a global partner with deep expertise in drug delivery solutions and drug device combination products, BD can help you bring your drug to market smoothly and efficiently by1:

  • Helping de-risk development activities
  • Providing robust system data on specific combination products to inform your development decisions
  • Supporting you in a complex regulatory environment for registration and regulatory filings

 

The impact of our extensive industry experience:

  • More than 11 billion BD glass barrels and stoppers sold from 2014 to 20181
  • More than 51 million BD autoinjectors sold from 2014 to 20181

About

At BD, we have built our services and capabilities around a deep understanding of the drug development process and the key objectives at each stage. Knowledgeable and responsible, our team offers the many capabilities you need beyond taking your product to market.

RIGHT SOLUTIONS, RIGHT TIME

Expert capabilities at each stage

No matter where you are in the process of combination product development, BD can help you reach your goals.

Learn more about our process for combination product development.

Request brochure

REALIZED BENEFITS

Efficient services to develop, de-risk
and accelerate delivery of your product

Each of our services is delivered intentionally and carefully to de-risk your development journey and accelerate the launch of your drug combination product on the market

  • Flexible offer

    Our goal : offer services tailored to your needs

  • Access to scientific testing experts

    Our goal : provide rapid and accurate answers to your questions

  • World-class container selection and validation

    Our goal : develop optimal solutions for your primary container and secondary device

  • Combination product knowledge and testing capabilities

    Our goal : ensure component and system performance consistency

  • Customizable protocols

    Our goal : deliver relevant results addressing your specific needs

  • GMP-compliant labs with state-of-the-art equipment

    Our goal : provide you with high-quality test results that can be leveraged in regulatory filings

Products

Develop. De-risk. Deliver.

BD Pharmaceutical Services and Solutions are designed to help you achieve your combination product goals, from development to launch.

Supporting pharmaceutical organizations in the development process with:

  • Fast access to low quantities** of drug delivery system component for development stage work to help support flexibility and streamline your device selection process.
  • Identification of recommended primary containers and secondary injection support devices for a drug's delivery requirements based on BD expertise in drug delivery solutions.
  • Proactive delivery of documentation to support combination product development and regulatory dossier preparation.
  • Support of technical problem solving, in primary container and secondary injection support devices and combination product development.
  • Research and development data* for BD PartnerPath™ delivery systems to help inform and de-risk combination product development.


*Available for select products and product systems
**Minimum purchase quantity at the lowest sterilized package configuration
‡Data and services are available for specific BD products and product configurations

Product engineering and device testing

To support customer system integration, we offer an evaluation of your delivery system functional performance testing, including:

  • Modeling of mechanical and material behaviors
  • Functional testing on customized systems
  • Functional dimension analysis

Evaluate primary container and drug interaction

We provide predictive tools, subvisible particle analysis, Tungsten studies, and extractable and leachable studies to help:

  • Support primary container choice
  • Assess leachable incompatibilities with tungsten, metal ion and organic leachable
  • Assess Interface incompatibilities (Drug degradation/alteration of the device functionality)
  • Assess what compounds associated with primary container could be extracted into the drug product

Evaluate combination product performance

To assist in evaluating device and drug combination product functional performance for needle-based injection systems, safety systems, and autoinjector systems, we offer:

  • Dose accuracy testing
  • Injection time (in air)
  • Activation and glide force testing
  • Additional testing capabilities
     

*Available for select products and product systems

Unite disparate systems and gain visibility

When your data is scattered, your operations can be too. Connected Medication Management leverages your EMR to create a comprehensive view of inventory on hand. That means managing fewer databases and gaining visibility so you can make valuable impacts on workflows across your organization and minimize medication diversion and adverse drug events. By having connected systems and bidirectional data exchange, predictive analytics can inform critical decision-making about care needs, help control carrying costs and avoid wasted inventory.

Webinar: From big data to results: Accelerating and sustaining medication inventory optimization

Leveraging IT investments with BD Connected Medication Management Solutions

Access to GMP production filling assembling, and labeling for not-for human-use small volumes, with services including:*±

Filling

  • Syringe filling in a clean atmosphere area
  • Glass and plastic syringes 1 mL to 50 mL
  • Terminal steam sterilization capable

Assembling

  • Assembling includes autoinjectors and safety needle shielding systems

Labeling

  • Labeling includes syringes and autoinjectors


*Available for select products and product systems
±Customer samples required

Supporting pharmaceutical organizations in the development process with:

  • Fast access to low quantities** of drug delivery system component for development stage work to help support flexibility and streamline your device selection process.
  • Identification of recommended primary containers and secondary injection support devices for a drug's delivery requirements based on BD expertise in drug delivery solutions.
  • Proactive delivery of documentation to support combination product development and regulatory dossier preparation.
  • Support of technical problem solving, in primary container and secondary injection support devices and combination product development.
  • Research and development data* for BD PartnerPath™ delivery systems to help inform and de-risk combination product development.


*Available for select products and product systems
**Minimum purchase quantity at the lowest sterilized package configuration
‡Data and services are available for specific BD products and product configurations

Products

EXPLORE OUR PRODUCTS

Products for all drug delivery needs

Services
Services

BD Pharmaceutical Services and Solutions are designed to help you achieve your combination product goals, from development to launch.

Learn more
BD PartnerPath program
BD PartnerPath program

BD PartnerPath™ Program aims to support pharmaceutical organizations that value speed to market in combination product development.1

Learn more
Overview

BD Medical - Pharmaceutical Systems Resource Library

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